The former NFL running back reportedly left his longtime wife – who was pregnant with twins at the time – for a much-younger NBC intern in 2010.
The three-time Oscar winner was already married with one child when she shocked Hollywood with her scandalous affair with a married film director in 1950.
The Oscar-winning actor was in his mid-40s – and married – when he met the teen actress who would become his mistress on the set of this movie in 1944.
The 1950s crooner was still married to actress Debbie Reynolds when he left her for her best friend in 1959.
The outspoken critic of President Bill Clinton left his second wife in 1999 for a three-decades-younger congressional clerk he had been cheating with for several years.
The former New York City mayor was still married to his second wife when he started showing up at public events with another woman.
The "Training Day" star was still married to his "Gattaca" co-star and mother of his two children when he reportedly began a relationship in 2004 with someone very close to their family.
King Henry VIII
The British monarch married Catherine of Aragon in 1509 but left her for a maid of honor when Catherine failed to produce a male heir.
The married governor shocked constituents in 1973 when he announced he was in love with another woman. What was his wife’s reaction?
The Republican senator returned to his first wife in 1973 after nearly six years as a prisoner of war but left her six years later for a much younger teacher from a wealthy family.
The "King of Cool" was at the height of his Hollywood fame (see his filmography) when left his wife of 15 years to be with his younger, up-and-coming co-star in a 1972 movie.
The future king of England – whose 1981 wedding to Diana Spencer was a global spectacle – reportedly carried on an affair for years with a woman he met at a polo match in 1970.
The country singer wed a backup dancer in 2002, but the marriage was over by 2009 amid reports of an affair with her Lifetime movie co-star.
The then-married former governor made headlines when he was reported missing and upon his return, confessed to spending time with his mistress abroad.
The "Beverly Hills, 90210" actress was still married to Charlie Shanian when she made a love connection with her co-star in a 2005 Lifetime movie.
The oft-married actress left husband Eddie Fisher – who left his spouse in 1959 for Taylor – in 1964 to began a turbulent relationship with her "Cleopatra" co-star.
The outspoken reality-show star and entrepreneur – now married to wife no. 3 – reportedly began a relationship in the late 1980s with a then-unknown “actress” while still married to his first wife.